3P8C
Structure and Control of the Actin Regulatory WAVE Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytoplasmic FMR1-interacting protein 1 | polymer | 1253 | 145363.8 | 1 | UniProt (Q7L576) Pfam (PF07159) Pfam (PF05994) | Homo sapiens (human) | Specifically Rac1-associated protein 1, Sra-1, p140sra-1 |
| 2 | B (B) | Nck-associated protein 1 | polymer | 1128 | 128940.7 | 1 | UniProt (Q9Y2A7) Pfam (PF09735) | Homo sapiens (human) | NAP 1, Membrane-associated protein HEM-2, p125Nap1 |
| 3 | C (D) | Wiskott-Aldrich syndrome protein family member 1 | polymer | 279 | 31930.8 | 1 | UniProt (Q92558) Pfam (PF02205) | Homo sapiens (human) | WASP family protein member 1, Protein WAVE-1, Verprolin homology domain-containing protein 1 |
| 4 | D (E) | Probable protein BRICK1 | polymer | 75 | 8756.9 | 1 | UniProt (Q8WUW1) | Homo sapiens (human) | |
| 5 | E (F) | Abl interactor 2 | polymer | 159 | 18112.6 | 1 | UniProt (B4DSN1) Pfam (PF07815) UniProt (by SIFTS) (Q9NYB9) | Homo sapiens (human) | |
| 6 | F (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | G, H, I, J, N... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 8 | K, L, M, Q (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 9 | R, S, T, U, V (A, B, D, E, F) | water | water | 18.0 | 957 | Chemie (HOH) |
Sequence modifications
D: 1 - 186 (UniProt: Q92558)
D: 205 - 279 (UniProt: Q92558)
F: 1 - 158 (UniProt: B4DSN1)
D: 205 - 279 (UniProt: Q92558)
| PDB | External Database | Details |
|---|---|---|
| Gly 187 | - | linker |
| Gly 188 | - | linker |
| Ser 189 | - | linker |
| Gly 190 | - | linker |
| Gly 191 | - | linker |
| Ser 192 | - | linker |
| Gly 193 | - | linker |
| Gly 194 | - | linker |
| Ser 195 | - | linker |
| Gly 196 | - | linker |
| Gly 197 | - | linker |
| Ser 198 | - | linker |
| Gly 199 | - | linker |
| Gly 200 | - | linker |
| Ser 201 | - | linker |
| Gly 202 | - | linker |
| Gly 203 | - | linker |
| Ser 204 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 333104.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 738.7 | |
| All* | Total formula weight | 333843.4 |
