3P1F
Crystal structure of the bromodomain of human CREBBP in complex with a hydroquinazolin ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CREB-binding protein | polymer | 119 | 14223.3 | 2 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (human) | |
| 2 | C, D, E, H, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 3 | F, M (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | G, N (A, B) | 3-methyl-3,4-dihydroquinazolin-2(1H)-one | non-polymer | 162.2 | 2 | Chemie (3PF) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28446.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 899.1 | |
| All* | Total formula weight | 29345.8 |
