Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1 |
| Chain | Residue |
| A | HOH100 |
| A | SER1079 |
| A | GLN1092 |
| A | MET1095 |
| A | GLU1099 |
| B | HOH33 |
| B | HOH62 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 3 |
| Chain | Residue |
| A | GLN1146 |
| A | GLN1152 |
| A | HOH67 |
| A | LYS1141 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | HOH54 |
| A | HOH225 |
| A | HOH239 |
| A | ASP1105 |
| A | PRO1106 |
| B | K1 |
| B | HOH98 |
| B | TRP1165 |
| B | LEU1166 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 2 |
| Chain | Residue |
| A | HOH187 |
| A | TRP1165 |
| A | LEU1166 |
| A | ASN1168 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 3PF A 1198 |
| Chain | Residue |
| A | HOH11 |
| A | PRO1110 |
| A | VAL1115 |
| A | ASN1168 |
| A | VAL1174 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 2 |
| Chain | Residue |
| A | PRO1106 |
| A | ARG1173 |
| A | PHE1177 |
| B | HOH226 |
| B | TRP1165 |
| B | TYR1175 |
| B | SER1179 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 4 |
| Chain | Residue |
| B | HOH23 |
| B | HOH25 |
| B | HOH65 |
| B | TRP1158 |
| B | LEU1159 |
| B | ASN1162 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 5 |
| Chain | Residue |
| B | HOH169 |
| B | ILE1128 |
| B | VAL1129 |
| B | LYS1130 |
| B | ASN1131 |
| B | ASN1163 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 7 |
| Chain | Residue |
| A | SER1179 |
| A | GLU1183 |
| A | GLU1186 |
| B | ARG1173 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 8 |
| Chain | Residue |
| A | TYR1175 |
| A | SER1179 |
| B | PRO1106 |
| B | ARG1173 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1 |
| Chain | Residue |
| A | EDO6 |
| A | HOH225 |
| B | HOH162 |
| B | TRP1165 |
| B | LEU1166 |
| B | ASN1168 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 3PF B 1198 |
| Chain | Residue |
| B | PRO1110 |
| B | VAL1115 |
| B | LEU1120 |
| B | ASN1168 |
| B | VAL1174 |
| B | HOH1199 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY |
| Chain | Residue | Details |
| A | SER1108-TYR1167 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 214 |
| Details | Domain: {"description":"Bromo","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 92 |
| Details | Region: {"description":"Interaction with histone","evidences":[{"source":"PubMed","id":"24361270","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Region: {"description":"Interaction with ASF1A","evidences":[{"source":"PubMed","id":"24616510","evidenceCode":"ECO:0000269"}]} |
