3OY1
Highly Selective c-Jun N-Terminal Kinase (JNK) 2 and 3 Inhibitors with In Vitro CNS-like Pharmacokinetic Properties
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 10 | polymer | 362 | 41799.4 | 1 | UniProt (P53779) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 10, MAPK 10, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | B (A) | 5-[2-(cyclohexylamino)pyridin-4-yl]-4-naphthalen-2-yl-2-(tetrahydro-2H-pyran-4-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one | non-polymer | 469.6 | 1 | Chemie (589) | |||
| 3 | C (A) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41799.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 469.6 | |
| All* | Total formula weight | 42268.9 |
