3OXG

human lysine methyltransferase Smyd3 in complex with AdoHcy (Form III)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SET and MYND domain-containing protein 3	polymer	464	53007.3	1	UniProt (Q9H7B4) Pfam (PF00856) Pfam (PF01753)	Homo sapiens (human)	Zinc finger MYND domain-containing protein 1
2	B, C, D (A)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
3	E (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)

Sequence modifications

A: 1 - 428 (UniProt: Q9H7B4)

PDB	External Database	Details
Met -35	-	expression tag
Gly -34	-	expression tag
Ser -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Leu -22	-	expression tag
Val -21	-	expression tag
Pro -20	-	expression tag
Arg -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Ala -14	-	expression tag
Ser -13	-	expression tag
Met -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gln -8	-	expression tag
Gln -7	-	expression tag
Met -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag
Asn 13	Lys 13	SEE REMARK 999
Arg 140	Lys 140	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53007.3
Non-Polymers*	Number of molecules	4
	Total formula weight	580.6
All*	Total formula weight	53588.0

*Water molecules are not included.