3OX1
X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribosyldihydronicotinamide dehydrogenase [quinone] | polymer | 231 | 25980.5 | 2 | UniProt (P16083) Pfam (PF02525) | Homo sapiens (human) | NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | G, H (B) | N-{2-[7-(methylsulfamoyl)naphthalen-1-yl]ethyl}acetamide | non-polymer | 306.4 | 2 | Chemie (695) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51961.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2314.7 | |
| All* | Total formula weight | 54275.7 |
