3OV1
Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Growth factor receptor-bound protein 2 | polymer | 117 | 13758.5 | 1 | UniProt (P62993) Pfam (PF00017) | Homo sapiens | Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash |
| 2 | B (B) | PYAC3CN | polymer | 5 | 497.4 | 1 | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 5 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
| His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14255.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 253.2 | |
| All* | Total formula weight | 14509.1 |
