3OSN
Structural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase Iota
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | 5'-D(*TP*CP*TP*(6OG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3' | polymer | 18 | 5506.6 | 2 | |||
| 2 | C (A) | DNA polymerase iota | polymer | 420 | 47027.3 | 1 | UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799) | Homo sapiens (human) | Eta2, RAD30 homolog B |
| 3 | D (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 4 | E, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | H, I, J (B, C, A) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58040.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 553.8 | |
| All* | Total formula weight | 58594.3 |
