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3OSK

Crystal structure of human CTLA-4 apo homodimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cytotoxic T-lymphocyte protein 4polymer13013976.92UniProt (P16410)
Pfam (PF07686)
Homo sapiens (human)Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4
2C, F
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
3D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4G, H
(A, B)
waterwater18.0228Chemie (HOH)
Sequence modifications
A, B: 1 - 126 (UniProt: P16410)
PDBExternal DatabaseDetails
Leu 127-expression tag
Val 128-expression tag
Pro 129-expression tag
Arg 130-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27953.9
Non-Polymers*Number of molecules4
Total formula weight626.6
All*Total formula weight28580.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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