3OSK
Crystal structure of human CTLA-4 apo homodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytotoxic T-lymphocyte protein 4 | polymer | 130 | 13976.9 | 2 | UniProt (P16410) Pfam (PF07686) | Homo sapiens (human) | Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4 |
| 2 | C, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 126 (UniProt: P16410)
| PDB | External Database | Details |
|---|---|---|
| Leu 127 | - | expression tag |
| Val 128 | - | expression tag |
| Pro 129 | - | expression tag |
| Arg 130 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27953.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 626.6 | |
| All* | Total formula weight | 28580.5 |






