3OMQ
Fragment-Based Design of novel Estrogen Receptor Ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor beta | polymer | 240 | 27109.1 | 2 | UniProt (Q92731) Pfam (PF00104) | Homo sapiens (human) | ER-beta, Nuclear receptor subfamily 3 group A member 2 |
| 2 | C, D (C, D) | Nuclear receptor coactivator 1 | polymer | 19 | 2234.5 | 2 | UniProt (Q15788) | NCoA-1, Steroid receptor coactivator 1, SRC-1, RIP160, Protein Hin-2, Renal carcinoma antigen NY-REN-52, Class E basic helix-loop-helix protein 74, bHLHe74 | |
| 3 | E, F (A, B) | 2-[(trifluoromethyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-6-ol | non-polymer | 281.3 | 2 | Chemie (W23) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58687.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 562.5 | |
| All* | Total formula weight | 59249.9 |
