3OG3

Crystal structure of an artificial thermostable (BA)8-barrel protein from identical half barrels

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Imidazole glycerol phosphate synthase subunit hisF	polymer	251	27316.2	1	UniProt (Q9X0C6) Pfam (PF00977) In PDB	Thermotoga maritima	IGP synthase cyclase subunit, IGP synthase subunit hisF, ImGP synthase subunit hisF, IGPS subunit hisF
2	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4		water	water		18.0	173	Chemie (HOH)

Sequence modifications

A: 2 - 98 (UniProt: Q9X0C6)

PDB	External Database	Details
Met 1	-	initiating methionine
Arg 3	Ala 124	engineered mutation
His 22	Tyr 143	engineered mutation

A: 99 - 219 (UniProt: Q9X0C6)

PDB	External Database	Details
His 143	Tyr 143	engineered mutation

A: 220 - 243 (UniProt: Q9X0C6)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27316.2
Non-Polymers*	Number of molecules	4
	Total formula weight	263.0
All*	Total formula weight	27579.3

*Water molecules are not included.