3OE1
Pyruvate decarboxylase variant Glu473Asp from Z. mobilis in complex with reaction intermediate 2-lactyl-ThDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate decarboxylase | polymer | 568 | 60976.3 | 4 | UniProt (P06672) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775) | Zymomonas mobilis | PDC |
| 2 | E, G, I, K (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, H, J, L (A, B, C, D) | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM | non-polymer | 513.4 | 4 | Chemie (TDL) | |||
| 4 | M, N (D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 1256 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 568 (UniProt: P06672)
| PDB | External Database | Details |
|---|---|---|
| Asp 473 | Glu 473 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 243905.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2334.9 | |
| All* | Total formula weight | 246240.1 |
