3ODI
Crystal structure of cyclophilin A in complex with Voclosporin E-ISA247
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... | Cyclophilin A | polymer | 165 | 18036.5 | 10 | UniProt (A8K220) Pfam (PF00160) UniProt (by SIFTS) (P62937) In PDB | Homo sapiens (human) | Peptidyl-prolyl cis-trans isomerase |
| 2 | B, D, F, H, J... | Voclosporin | polymer | 11 | 1232.6 | 10 | NOR (NOR00033) | Tolypocladium inflatum | E-ISA247, ISATX-247, LUVENIQ |
| 3 | water | water | 18.0 | 1510 | Chemie (HOH) |
Sequence modifications
B, D, F, H, J, L, N, P, R, T: 1 - 11 (NOR: NOR00033)
| PDB | External Database | Details |
|---|---|---|
| Xxa 5 | Bmt 5 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 192691.4 | |
| All* | Total formula weight | 192691.4 |
