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3OB1

Crystal structure of c-Cbl TKB domain in complex with double phosphorylated Spry2 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
12-meric peptide from Protein sprouty homolog 2polymer121555.41UniProt (O43597)Homo sapiensSpry-2
2B
(B)
E3 ubiquitin-protein ligase CBLpolymer32938192.11UniProt (P22681)
Pfam (PF02262)
Pfam (PF02761)
Pfam (PF02762)
Homo sapiens (human)Signal transduction protein CBL, Proto-oncogene c-Cbl, Casitas B-lineage lymphoma proto-oncogene, RING finger protein 55
3C, D
(A, B)
waterwater18.0162Chemie (HOH)
Sequence modifications
B: 25 - 351 (UniProt: P22681)
PDBExternal DatabaseDetails
Gly 23-expression tag
Ser 24-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight39747.5
All*Total formula weight39747.5
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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