3OA6

Human MSL3 Chromodomain bound to DNA and H4K20me1 peptide

Replaces:  3M9P

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Male-specific lethal 3 homolog	polymer	110	13101.1	2	UniProt (Q8N5Y2) Pfam (PF11717) Pfam (PF22732)	Homo sapiens (human)	Male-specific lethal-3 protein-like 1, MSL3-like 1, Male-specific lethal-3 homolog 1
2	C, E (C, E)	DNA (5'-D(*GP*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3')	polymer	16	4947.2	2
3	D, F (D, F)	DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3')	polymer	16	4849.2	2
4	G (G)	H4 peptide monomethylated at lysine 20	polymer	24	2687.2	1
5	H (B)	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
6	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	108	Chemie (HOH)

Sequence modifications

A, B: 1 - 101 (UniProt: Q8N5Y2)

PDB	External Database	Details
Met -8	-	expression tag
Lys -7	-	expression tag
Lys -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	48482.2
Non-Polymers*	Number of molecules	1
	Total formula weight	69.1
All*	Total formula weight	48551.3

*Water molecules are not included.