3O9E
Crystal Structure of wild-type HIV-1 Protease in complex with af60
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pol polyprotein | polymer | 99 | 10815.8 | 2 | UniProt (Q90K99) Pfam (PF00077) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | C, D, E, F (A) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | H (A) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-1-benzyl-2-hydroxypropyl]carbamate | non-polymer | 575.7 | 1 | Chemie (A60) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q90K99)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1014.6 | |
| All* | Total formula weight | 22646.2 |
