3O6T
Mycobacterium tuberculosis thioredoxin C C40S mutant in Complex with Quinol Inhibitor PMX464
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thioredoxin | polymer | 118 | 12685.5 | 4 | UniProt (P0A616) Pfam (PF00085) UniProt (by SIFTS) (P9WG67) | Mycobacterium tuberculosis | thioredoxin C, Trx, MPT46 |
| 2 | E, G (A, C) | 4-(1,3-benzothiazol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-one | non-polymer | 243.3 | 2 | Chemie (PX5) | |||
| 3 | F, H (A, C) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 116 (UniProt: P0A616)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ser 40 | Cys 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 50742.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 786.9 | |
| All* | Total formula weight | 51528.9 |
