3O6T

Mycobacterium tuberculosis thioredoxin C C40S mutant in Complex with Quinol Inhibitor PMX464

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009055	molecular_function	electron transfer activity
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0015035	molecular_function	protein-disulfide reductase activity
A	0015036	molecular_function	disulfide oxidoreductase activity
A	0015038	molecular_function	glutathione disulfide oxidoreductase activity
A	0045454	biological_process	cell redox homeostasis
B	0003824	molecular_function	catalytic activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0009055	molecular_function	electron transfer activity
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0015035	molecular_function	protein-disulfide reductase activity
B	0015036	molecular_function	disulfide oxidoreductase activity
B	0015038	molecular_function	glutathione disulfide oxidoreductase activity
B	0045454	biological_process	cell redox homeostasis
C	0003824	molecular_function	catalytic activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0009055	molecular_function	electron transfer activity
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0015035	molecular_function	protein-disulfide reductase activity
C	0015036	molecular_function	disulfide oxidoreductase activity
C	0015038	molecular_function	glutathione disulfide oxidoreductase activity
C	0045454	biological_process	cell redox homeostasis
D	0003824	molecular_function	catalytic activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0009055	molecular_function	electron transfer activity
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0015035	molecular_function	protein-disulfide reductase activity
D	0015036	molecular_function	disulfide oxidoreductase activity
D	0015038	molecular_function	glutathione disulfide oxidoreductase activity
D	0045454	biological_process	cell redox homeostasis

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX5 A 117

Chain	Residue
A	CYS37
A	PRO39
A	ILE80
B	THR35
B	TRP36
B	ASP66

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PGE A 118

Chain	Residue
D	SER23
A	LEU22
A	SER23
D	LEU22

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PX5 C 117

Chain	Residue
B	MET42
C	CYS37
C	PRO39
C	ILE80
D	TRP36
D	ASP66

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PGE C 118

Chain	Residue
B	LEU22
C	LEU22
C	HOH155

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