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3O5Z

Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Phosphatidylinositol 3-kinase regulatory subunit betapolymer909811.12UniProt (O00459)Homo sapiens (human)PtdIns-3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PtdIns-3-kinase regulatory subunit p85-beta, PI3-kinase subunit p85-beta
2C, D
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3E
(B)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
4F, G
(A, B)
waterwater18.023Chemie (HOH)
Sequence modifications
A, B: 1 - 85 (UniProt: O00459)
PDBExternal DatabaseDetails
Gly -4-expression tag
Pro -3-expression tag
Leu -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight19622.3
Non-Polymers*Number of molecules3
Total formula weight189.1
All*Total formula weight19811.3
*Water molecules are not included.

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PDB entries from 2025-08-06

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