3O5Z
Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Phosphatidylinositol 3-kinase regulatory subunit beta | polymer | 90 | 9811.1 | 2 | UniProt (O00459) In PDB | Homo sapiens (human) | PtdIns-3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PtdIns-3-kinase regulatory subunit p85-beta, PI3-kinase subunit p85-beta |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | B | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 85 (UniProt: O00459)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | EXPRESSION TAG |
| Pro -3 | - | EXPRESSION TAG |
| Leu -2 | - | EXPRESSION TAG |
| Gly -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19622.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 189.1 | |
| All* | Total formula weight | 19811.3 |
