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3O4R

Crystal Structure of Human Dehydrogenase/Reductase (SDR family) member 4 (DHRS4)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Dehydrogenase/reductase SDR family member 4polymer26127690.94UniProt (Q9BTZ2)
Pfam (PF13561)
Homo sapiens (human)Short-chain dehydrogenase/reductase family member 4, NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, PHCR, CR, Peroxisomal short-chain alcohol dehydrogenase, PSCD, NADPH-dependent retinol dehydrogenase/reductase, NRDR, humNRDR, SCAD-SRL
2E, H, L, N
(A, B, C, D)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.44Chemie (NAP)
3F, I, J, O
(A, B, D)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
4G
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
5K, M
(B, C)
GLYCEROLnon-polymer92.12Chemie (GOL)
6P, Q, R, S
(A, B, C, D)
waterwater18.0606Chemie (HOH)
Sequence modifications
A, B, C, D: 19 - 278 (UniProt: Q9BTZ2)
PDBExternal DatabaseDetails
Ser 18-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight110763.5
Non-Polymers*Number of molecules11
Total formula weight3644.4
All*Total formula weight114407.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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