3O47

Crystal structure of ARFGAP1-ARF1 fusion protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1	polymer	329	37945.1	2	UniProt (Q8N6T3) UniProt (P84077) Pfam (PF01412) Pfam (PF00025)	Homo sapiens (human)	ARF GAP 1, ADP-ribosylation factor 1 GTPase-activating protein, ARF1 GAP, ARF1-directed GTPase-activating protein
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (A, B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)

Sequence modifications

A, B: 1 - 140 (UniProt: Q8N6T3)

PDB	External Database	Details
Met -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

A, B: 141 - 311 (UniProt: P84077)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75890.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1017.2
All*	Total formula weight	76907.4

*Water molecules are not included.