3O0I
Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor PU-H54
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HSP90AA1 protein | polymer | 256 | 28773.1 | 1 | UniProt (Q2VPJ6) Pfam (PF13589) UniProt (by SIFTS) (P07900) In PDB | Homo sapiens (human) | |
2 | A | 8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine | non-polymer | 337.4 | 1 | Chemie (P54) | |||
3 | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 1 - 236 (UniProt: Q2VPJ6)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28773.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 337.4 | |
All* | Total formula weight | 29110.6 |