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3NYN

Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
G protein-coupled receptor kinase 6polymer57665981.82UniProt (P43250)
Pfam (PF00615)
Pfam (PF00069)
Homo sapiens (human)G protein-coupled receptor kinase GRK6
2C, L
(A, B)
SANGIVAMYCINnon-polymer309.32Chemie (SGV)
3D, E, F, G, H...
(A, B)
SULFATE IONnon-polymer96.114Chemie (SO4)
4I, R
(A, B)
(R,R)-2,3-BUTANEDIOLnon-polymer90.12Chemie (BU3)
5U, V
(A, B)
waterwater18.012Chemie (HOH)
Sequence modifications
A, B: 2 - 576 (UniProt: P43250)
PDBExternal DatabaseDetails
Ace 1-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight131963.6
Non-Polymers*Number of molecules18
Total formula weight2143.7
All*Total formula weight134107.2
*Water molecules are not included.

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PDB entries from 2025-07-02

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