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3NYN

Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
G protein-coupled receptor kinase 6polymer57665981.82UniProt (P43250)
Pfam (PF00615)
Pfam (PF00069)
Homo sapiens (human)G protein-coupled receptor kinase GRK6
2C, L
(A, B)
SANGIVAMYCINnon-polymer309.32Chemie (SGV)
PubChem (16760643)
PubChem (5153)
PubChem (14978)
PubChem (44330426)
PubChem (57685061)
PubChem (46875748)
PubChem (70829033)
PubChem (3007220)
PubChem (89687375)
PubChem (92209899)
PubChem (92209900)
PubChem (92209901)
PubChem (6712998)
PubChem (101037982)
PubChem (10403057)
PubChem (10448038)
PubChem (142650208)
PubChem (162968206)
3D, E, F, G, H...
(A, B)
SULFATE IONnon-polymer96.114Chemie (SO4)
4I, R
(A, B)
(R,R)-2,3-BUTANEDIOLnon-polymer90.12Chemie (BU3)
5U, V
(A, B)
waterwater18.012Chemie (HOH)
Sequence modifications
A, B: 2 - 576 (UniProt: P43250)
PDBExternal DatabaseDetails
Ace 1-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight131963.6
Non-Polymers*Number of molecules18
Total formula weight2143.7
All*Total formula weight134107.2
*Water molecules are not included.

253091

PDB entries from 2026-05-06

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