3NWY

Structure and allosteric regulation of the uridine monophosphate kinase from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Uridylate kinase	polymer	281	29625.9	6	UniProt (P65929) Pfam (PF00696) UniProt (by SIFTS) (P9WHK5)	Mycobacterium tuberculosis	UK, Uridine monophosphate kinase, UMP kinase, UMPK
2	G, H, J, K, L... (A, B, C, D, E...)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	6	Chemie (GTP)
3	I (B)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP)
4	N, O, P, Q, R... (A, B, C, D, E...)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 261 (UniProt: P65929)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	177755.4
Non-Polymers*	Number of molecules	7
	Total formula weight	3543.2
All*	Total formula weight	181298.6

*Water molecules are not included.