3NWU
Substrate induced remodeling of the active site regulates HtrA1 activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine protease HTRA1 | polymer | 227 | 24876.4 | 3 | UniProt (Q92743) Pfam (PF13365) | Homo sapiens (human) | L56, Serine protease 11 |
| 2 | D, E, F (A, B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) |
Sequence modifications
A, B, C: 158 - 375 (UniProt: Q92743)
| PDB | External Database | Details |
|---|---|---|
| Met 157 | - | initiating methionine |
| Leu 376 | - | expression tag |
| Glu 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74629.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 74917.4 |
