3NR2

Crystal structure of Caspase-6 zymogen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Caspase-6	polymer	294	33701.5	2	UniProt (P55212) Pfam (PF00656) In PDB	Homo sapiens (human)	CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11

Sequence modifications

A, B: 24 - 293 (UniProt: P55212)

PDB	External Database	Details
Met 8	-	expression tag
Ala 9	-	expression tag
Ser 10	-	expression tag
Met 11	-	expression tag
Thr 12	-	expression tag
Gly 13	-	expression tag
Gly 14	-	expression tag
Gln 15	-	expression tag
Gln 16	-	expression tag
Met 17	-	expression tag
Gly 18	-	expression tag
Arg 19	-	expression tag
Asp 20	-	expression tag
Pro 21	-	expression tag
Asn 22	-	expression tag
Ser 23	-	expression tag
Val 93	Ala 93	engineered mutation
Ala 163	Cys 163	engineered mutation
Leu 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67402.9
All*	Total formula weight	67402.9

*Water molecules are not included.