3NQJ

Crystal structure of (CENP-A/H4)2 heterotetramer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Histone H3-like centromeric protein A	polymer	82	9379.0	1	UniProt (P49450) Pfam (PF00125)	Homo sapiens (human)	Centromere protein A, CENP-A, Centromere autoantigen A
2	B (B)	Histone H4	polymer	84	9540.3	1	UniProt (P62805) Pfam (PF15511)	Homo Sapiens (Human)
3	C, D, E, F (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4	G, H (A, B)	water	water		18.0	136	Chemie (HOH)

Sequence modifications

A: 60 - 140 (UniProt: P49450)

PDB	External Database	Details
Met 59	-	insertion

B: 20 - 102 (UniProt: P62805)

PDB	External Database	Details
Met 19	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18919.3
Non-Polymers*	Number of molecules	4
	Total formula weight	379.9
All*	Total formula weight	19299.2

*Water molecules are not included.