3NMX

Crystal structure of APC complexed with Asef

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	APC variant protein	polymer	354	39268.2	3	UniProt (Q4LE70) Pfam (PF18797) Pfam (PF00514) UniProt (by SIFTS) (P25054) In PDB	Homo sapiens (human)	Adenomatous Polyposis Coli
2	D, E, F	Rho guanine nucleotide exchange factor 4	polymer	25	2552.6	3	UniProt (Q9NR80) In PDB	Homo sapiens	APC-stimulated guanine nucleotide exchange factor, Asef
3		water	water		18.0	517	Chemie (HOH)

Sequence modifications

A, B, C: 407 - 751 (UniProt: Q4LE70)

PDB	External Database	Details
Met 398	-	expression tag
Gly 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
Met 406	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	125462.7
All*	Total formula weight	125462.7

*Water molecules are not included.