3NMX
Crystal structure of APC complexed with Asef
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | APC variant protein | polymer | 354 | 39268.2 | 3 | UniProt (Q4LE70) Pfam (PF18797) Pfam (PF00514) UniProt (by SIFTS) (P25054) | Homo sapiens (human) | Adenomatous Polyposis Coli |
| 2 | D, E, F (D, E, F) | Rho guanine nucleotide exchange factor 4 | polymer | 25 | 2552.6 | 3 | UniProt (Q9NR80) | Homo sapiens | APC-stimulated guanine nucleotide exchange factor, Asef |
| 3 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence modifications
A, B, C: 407 - 751 (UniProt: Q4LE70)
| PDB | External Database | Details |
|---|---|---|
| Met 398 | - | expression tag |
| Gly 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| Met 406 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 125462.7 | |
| All* | Total formula weight | 125462.7 |
