3NLB
Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Chk1 | polymer | 297 | 34148.1 | 1 | UniProt (O14757) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (A) | 3-methyl-5-[5-(1-methylethyl)-1H-benzimidazol-2-yl]-N-(1-methylpiperidin-4-yl)-1H-pyrazole-4-carboxamide | non-polymer | 380.5 | 1 | Chemie (5BE) | |||
| 3 | C (A) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: O14757)
| PDB | External Database | Details |
|---|---|---|
| His 290 | - | expression tag |
| His 291 | - | expression tag |
| His 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34148.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 380.5 | |
| All* | Total formula weight | 34528.6 |
