3NLB
Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase Chk1 | polymer | 297 | 34148.1 | 1 | UniProt (O14757) Pfam (PF00069) In PDB | Homo sapiens (human) | |
2 | A | 3-methyl-5-[5-(1-methylethyl)-1H-benzimidazol-2-yl]-N-(1-methylpiperidin-4-yl)-1H-pyrazole-4-carboxamide | non-polymer | 380.5 | 1 | Chemie (5BE) | |||
3 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: O14757)
PDB | External Database | Details |
---|---|---|
His 290 | - | expression tag |
His 291 | - | expression tag |
His 292 | - | expression tag |
His 293 | - | expression tag |
His 294 | - | expression tag |
His 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34148.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 380.5 | |
All* | Total formula weight | 34528.6 |