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3NGQ

Crystal structure of the human CNOT6L nuclease domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CCR4-NOT transcription complex subunit 6-likepolymer39845156.51UniProt (Q96LI5)
Pfam (PF03372)
Homo sapiens (human)CNOT6L, CARBON CATABOLITE REPRESSOR PROTEIN 4 HOMOLOG B
2B
(A)
3-PYRIDINIUM-1-YLPROPANE-1-SULFONATEnon-polymer201.21Chemie (1PS)
3C, D
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E
(A)
waterwater18.0256Chemie (HOH)
Sequence modifications
A: 158 - 555 (UniProt: Q96LI5)
PDBExternal DatabaseDetails
Glu 501Leu 501engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight45156.5
Non-Polymers*Number of molecules3
Total formula weight249.9
All*Total formula weight45406.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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