3NG8
Crystal structure of an abridged SER TO ALA MUTANT OF THE MATURE ECTODOMAIN of the human receptor-type protein-tyrosine phosphatase ICA512/IA-2 at PH 8.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-type tyrosine-protein phosphatase-like N | polymer | 89 | 9621.9 | 2 | UniProt (Q16849) Pfam (PF11548) | Homo sapiens (human) | R-PTP-N, PTP IA-2, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3 |
| 2 | C (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A, B: 470 - 558 (UniProt: Q16849)
| PDB | External Database | Details |
|---|---|---|
| Ala 508 | Ser 508 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19243.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 19283.9 |
