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3NEX

V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer11612735.32UniProt (P02766)
Pfam (PF00576)
Homo sapiens (human)Prealbumin, TBPA, TTR, ATTR
2C, E
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
3D, F
(A, B)
[4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACIDnon-polymer376.42Chemie (G24)
4G, H
(A, B)
waterwater18.0210Chemie (HOH)
Sequence modifications
A, B: 10 - 125 (UniProt: P02766)
PDBExternal DatabaseDetails
Met 30Val 50engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25470.6
Non-Polymers*Number of molecules4
Total formula weight937.1
All*Total formula weight26407.6
*Water molecules are not included.

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PDB entries from 2025-07-16

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