3NEX
V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 116 | 12735.3 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | Prealbumin, TBPA, TTR, ATTR |
| 2 | C, E (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D, F (A, B) | [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID | non-polymer | 376.4 | 2 | Chemie (G24) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 125 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met 30 | Val 50 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25470.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 937.1 | |
| All* | Total formula weight | 26407.6 |
