3N9U
Crystal Structure of the Complex between the 25 kDa Subunit and the 59 kDa Subunit (RRM domain) of Human Cleavage Factor Im
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cleavage and polyadenylation specificity factor subunit 5 | polymer | 230 | 26720.7 | 2 | UniProt (O43809) Pfam (PF13869) In PDB | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 25 kDa subunit, CPSF 25 kDa subunit, Pre-mRNA cleavage factor Im 25 kDa subunit, Nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21 |
| 2 | C, I | Cleavage and polyadenylation specificity factor subunit 7 | polymer | 156 | 17711.0 | 2 | UniProt (Q8N684) Pfam (PF00076) In PDB | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 59 kDa subunit, CPSF 59 kDa subunit, Pre-mRNA cleavage factor Im 59 kDa subunit |
| 3 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 227 (UniProt: O43809)
C, I: 50 - 182 (UniProt: Q8N684)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Val 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Leu 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Thr 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Asn 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Tyr 16 | - | expression tag |
| Phe 17 | - | expression tag |
| Gln 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Met 20 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| Ser 34 | - | expression tag |
| Ser 35 | - | expression tag |
| Gly 36 | - | expression tag |
| Val 37 | - | expression tag |
| Asp 38 | - | expression tag |
| Leu 39 | - | expression tag |
| Gly 40 | - | expression tag |
| Thr 41 | - | expression tag |
| Glu 42 | - | expression tag |
| Asn 43 | - | expression tag |
| Leu 44 | - | expression tag |
| Tyr 45 | - | expression tag |
| Phe 46 | - | expression tag |
| Gln 47 | - | expression tag |
| Ser 48 | - | expression tag |
| Met 49 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88863.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 89139.6 |
