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3N45

Human FPPS complex with FBS_04 and zoledronic acid/MG2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1FFARNESYL PYROPHOSPHATE SYNTHASEpolymer35040183.91UniProt (P14324)
Pfam (PF00348)
In PDB
Homo sapiens (human)FPP synthase, FPS, Farnesyl diphosphate synthase, Dimethylallyltranstransferase, Geranyltranstransferase
2F(2S)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acidnon-polymer297.31Chemie (3N3)
3FZOLEDRONIC ACIDnon-polymer272.11Chemie (ZOL)
4FMAGNESIUM IONnon-polymer24.33Chemie (MG)
5FPHOSPHATE IONnon-polymer95.02Chemie (PO4)
6waterwater18.0156Chemie (HOH)
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDBExternal DatabaseDetails
Gly 4-expression tag
Pro 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40183.9
Non-Polymers*Number of molecules7
Total formula weight832.3
All*Total formula weight41016.1
*Water molecules are not included.

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