3N3Y
Crystal structure of Thymidylate Synthase X (ThyX) from Helicobacter pylori with FAD and dUMP at 2.31A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thymidylate synthase thyX | polymer | 216 | 24872.4 | 4 | UniProt (Q5UVJ4) Pfam (PF02511) | Helicobacter pylori | Thymidylate Synthase X, thyX, TS, TSase |
| 2 | E, G, H, J, L (A, B, C, D) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 5 | Chemie (UMP) | |||
| 3 | F, I, K, M (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 208 (UniProt: Q5UVJ4)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99489.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4683.1 | |
| All* | Total formula weight | 104172.6 |
