3N3M

Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 6-amino-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotidine 5'-phosphate decarboxylase	polymer	342	39899.5	2	UniProt (Q8IJH3) Pfam (PF00215)	Plasmodium falciparum
2	C, D (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
3	E, I, J, K (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4	F (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	G, L (A, B)	6-AMINOURIDINE 5'-MONOPHOSPHATE	non-polymer		339.2	2	Chemie (NUP)
6	H (B)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
7	M, N (A, B)	water	water		18.0	597	Chemie (HOH)

Sequence modifications

A, B: 1 - 322 (UniProt: Q8IJH3)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79798.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1414.1
All*	Total formula weight	81213.0

*Water molecules are not included.