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3N0T

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Dipeptidyl peptidase 2polymer46952043.34UniProt (Q9UHL4)
Pfam (PF05577)
Homo sapiens (human)Dipeptidyl peptidase II, DPP II, Dipeptidyl aminopeptidase II, Quiescent cell proline dipeptidase, Dipeptidyl peptidase 7
2E, F, G, H
(A, B, C, D)
(3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diaminenon-polymer185.34Chemie (OPY)
3I, J, K, L
(A, B, C, D)
waterwater18.0248Chemie (HOH)
Sequence modifications
A, B, C, D: 28 - 492 (UniProt: Q9UHL4)
PDBExternal DatabaseDetails
Gly 24-expression tag
Ala 25-expression tag
Met 26-expression tag
Asp 27-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight208173.4
Non-Polymers*Number of molecules4
Total formula weight741.1
All*Total formula weight208914.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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