3N0E
Crystal structure of WDR5 mutant (W330Y)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 315 | 34605.2 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | WDR5, BMP2-induced 3-kb gene protein |
| 2 | B (A) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 31 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Gln 22 | - | expression tag |
| Gln 23 | - | expression tag |
| Met 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Arg 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Glu 29 | - | expression tag |
| Phe 30 | - | expression tag |
| Tyr 330 | Trp 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34605.2 | |
| All* | Total formula weight | 34605.2 |
