3MY1
Structure of CDK9/cyclinT1 in complex with DRB
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cell division protein kinase 9 | polymer | 331 | 38054.1 | 1 | UniProt (P50750) Pfam (PF00069) In PDB | Homo sapiens (human) | Cyclin-dependent kinase 9, Serine/threonine-protein kinase PITALRE, Cell division cycle 2-like protein kinase 4, C-2K |
2 | B | Cyclin-T1 | polymer | 260 | 30119.4 | 1 | UniProt (O60563) Pfam (PF00134) Pfam (PF21797) In PDB | Homo sapiens (human) | Cyclin-T, CycT1 |
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | A | 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole | non-polymer | 319.1 | 1 | Chemie (RFZ) | |||
6 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A: 2 - 330 (UniProt: P50750)
B: 2 - 259 (UniProt: O60563)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Pro 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Pro 1 | - | expression tag |
Arg 77 | Gln 77 | engineered mutation |
Gly 96 | Glu 96 | engineered mutation |
Leu 241 | Phe 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68173.5 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 874.6 | |
All* | Total formula weight | 69048.1 |