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3MXW

Crystal structure Sonic hedgehog bound to the 5E1 fab fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sonic hedgehog proteinpolymer16919122.51UniProt (Q15465)
Pfam (PF01085)
Homo sapiens (human)SHH, HHG-1, Sonic hedgehog protein N-product, Sonic hedgehog protein C-product
2B
(L)
5E1 light chainpolymer21423507.11Homo sapiens (human)
3C
(H)
5E1 heavy chainpolymer22023816.61Homo sapiens (human)
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E, F
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
6G, H, I
(A, L)
SULFATE IONnon-polymer96.13Chemie (SO4)
7J, K, L
(A, L, H)
waterwater18.0423Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight66446.2
Non-Polymers*Number of molecules6
Total formula weight433.8
All*Total formula weight66880.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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