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3MXA

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
scV3V2(G19S)polymer36240968.71Chlamydomonas reinhardtii
2B
(C)
DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3')polymer144261.81
3C
(D)
DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3')polymer103014.01
4D
(E)
DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*C)-3')polymer144311.81
5E
(F)
DNA (5'-D(P*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3')polymer103062.01
6F, G, H
(A)
MANGANESE (II) IONnon-polymer54.93Chemie (MN)
7I, J, K
(A)
ETHANOLnon-polymer46.13Chemie (EOH)
8L
(C)
PENTAETHYLENE GLYCOLnon-polymer238.31Chemie (1PE)
9M, N, O, P, Q
(A, C, D, E, F)
waterwater18.0120Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight55618.3
Non-Polymers*Number of molecules7
Total formula weight541.3
All*Total formula weight56159.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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