3MWS
Crystal Structure of Group N HIV-1 Protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 Protease | polymer | 99 | 10881.7 | 2 | UniProt (Q673V0) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q673V0)
| PDB | External Database | Details |
|---|---|---|
| Ala 95 | Cys 156 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21763.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 583.1 | |
| All* | Total formula weight | 22346.4 |
