3MUU
Crystal structure of the Sindbis virus E2-E1 heterodimer at low pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Structural polyprotein | polymer | 750 | 82617.7 | 6 | UniProt (P03316) Pfam (PF00943) Pfam (PF01589) | Sindbis virus (SINV) | p130, Capsid protein, Coat protein, C, p62, E3/E2, E3 protein, Spike glycoprotein E3, E2 envelope glycoprotein, Spike glycoprotein E2, 6K protein, E1 envelope glycoprotein, Spike glycoprotein E1 |
| 2 | G, I, J, K, L... (G, I, J, K, L...) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 8 | In PDB GlyTouCan (G81315DD) | |||
| 3 | H, P, R (H, P, R) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 4 | N (N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A, B, C, D, E, F: 1 - 344 (UniProt: P03316)
A, B, C, D, E, F: 361 - 740 (UniProt: P03316)
A, B, C, D, E, F: 361 - 740 (UniProt: P03316)
| PDB | External Database | Details |
|---|---|---|
| Gly 345 | - | linker |
| Gly 346 | - | linker |
| Gly 347 | - | linker |
| Ser 348 | - | linker |
| Trp 349 | - | linker |
| Ser 350 | - | linker |
| His 351 | - | linker |
| Pro 352 | - | linker |
| Gln 353 | - | linker |
| Phe 354 | - | linker |
| Glu 355 | - | linker |
| Lys 356 | - | linker |
| Gly 357 | - | linker |
| Gly 358 | - | linker |
| Gly 359 | - | linker |
| Gly 360 | - | linker |
| Gly 435 | Asp 881 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 495706.3 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 9308.5 | |
| All* | Total formula weight | 505014.8 |
