3MTC

Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Type II inositol-1,4,5-trisphosphate 5-phosphatase	polymer	313	36201.1	1	UniProt (P32019) Pfam (PF22669) In PDB	Homo sapiens (human)	Phosphoinositide 5-phosphatase, 5PTase, 75 kDa inositol polyphosphate-5-phosphatase
2	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	(2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate	non-polymer		666.6	1	Chemie (PIF)
5	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7		water	water		18.0	225	Chemie (HOH)

Sequence modifications

A: 259 - 563 (UniProt: P32019)

PDB	External Database	Details
Met 258	-	expression tag
Ala 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag
His 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag
His 570	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36201.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1006.6
All*	Total formula weight	37207.7

*Water molecules are not included.