3MTC
Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Type II inositol-1,4,5-trisphosphate 5-phosphatase | polymer | 313 | 36201.1 | 1 | UniProt (P32019) Pfam (PF22669) | Homo sapiens (human) | Phosphoinositide 5-phosphatase, 5PTase, 75 kDa inositol polyphosphate-5-phosphatase |
| 2 | B, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate | non-polymer | 666.6 | 1 | Chemie (PIF) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | H (A) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 259 - 563 (UniProt: P32019)
| PDB | External Database | Details |
|---|---|---|
| Met 258 | - | expression tag |
| Ala 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36201.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1006.6 | |
| All* | Total formula weight | 37207.7 |
