3MSX
Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA | polymer | 180 | 20363.3 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | Rho cDNA clone 12, h12 |
| 2 | B (B) | Rho GTPase-activating protein 20 | polymer | 201 | 22579.0 | 1 | UniProt (Q9P2F6) Pfam (PF00620) | Homo sapiens (human) | Rho-type GTPase-activating protein 20 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E (A) | TRIFLUOROMAGNESATE | non-polymer | 81.3 | 1 | Chemie (MGF) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 1 - 180 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42942.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.8 | |
| All* | Total formula weight | 43491.1 |
