3MSX
Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA | polymer | 180 | 20363.3 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | Rho cDNA clone 12, h12 |
| 2 | B (B) | Rho GTPase-activating protein 20 | polymer | 201 | 22579.0 | 1 | UniProt (Q9P2F6) Pfam (PF00620) | Homo sapiens (human) | Rho-type GTPase-activating protein 20 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | TRIFLUOROMAGNESATE | non-polymer | 81.3 | 1 | Chemie (MGF) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 1 - 180 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Asn 25 | Phe 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42942.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 548.8 | |
| All* | Total formula weight | 43491.1 |
