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3MR5

Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (human)RAD30 homolog A, Xeroderma pigmentosum variant type protein
2TDNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3')polymer123974.61
3PDNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3')polymer92723.81
4A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosinenon-polymer506.22Chemie (XG4)
5AMAGNESIUM IONnon-polymer24.32Chemie (MG)
6A, TGLYCEROLnon-polymer92.111Chemie (GOL)
7waterwater18.0367Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight55316.2
Non-Polymers*Number of molecules15
Total formula weight2074.0
All*Total formula weight57390.2
*Water molecules are not included.

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PDB entries from 2024-05-01

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