3MI2
Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Uridine 5'-monophosphate synthase | polymer | 279 | 30504.2 | 2 | UniProt (P11172) Pfam (PF00215) In PDB | Homo sapiens (human) | UMP synthase, Orotate phosphoribosyltransferase, OPRTase, Orotidine 5'-phosphate decarboxylase, OMPdecase |
2 | A, B | (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol | non-polymer | 339.2 | 2 | Chemie (PFU) | |||
3 | water | water | 18.0 | 692 | Chemie (HOH) |
Sequence modifications
A, B: 34 - 291 (UniProt: P11172)
PDB | External Database | Details |
---|---|---|
Met 13 | - | expression tag |
Gly 14 | - | expression tag |
Ser 15 | - | expression tag |
Ser 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
His 19 | - | expression tag |
His 20 | - | expression tag |
His 21 | - | expression tag |
His 22 | - | expression tag |
Ser 23 | - | expression tag |
Ser 24 | - | expression tag |
Gly 25 | - | expression tag |
Leu 26 | - | expression tag |
Val 27 | - | expression tag |
Pro 28 | - | expression tag |
Arg 29 | - | expression tag |
Gly 30 | - | expression tag |
Ser 31 | - | expression tag |
His 32 | - | expression tag |
Met 33 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 61008.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 678.4 | |
All* | Total formula weight | 61686.7 |