3MI0

Crystal Structure of Mycobacterium Tuberculosis Proteasome at 2.2 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, AA, B, D, F... (A, B, D, F, I...)	Proteasome subunit alpha	polymer	248	26911.0	14	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1)	Mycobacterium tuberculosis	Proteasome core protein prcA, 20S proteasome alpha subunit
2	BA, C, E, G, H... (C, E, G, H, J...)	Proteasome subunit beta	polymer	240	25274.3	14	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9)	Mycobacterium tuberculosis	Proteasome core protein prcB, 20S proteasome beta subunit
3	AB, AC, AD, AE, AF... (F, K, P, V, 2...)	DIMETHYLFORMAMIDE	non-polymer		73.1	123	Chemie (DMF)
4	ED, IC, IE, IF, MB... (P, L, V, 2, G...)	(2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-ethyl-3-hydroxy-3-methyl-5-oxopyrrolidine-2-carbaldehyde	non-polymer		281.3	14	Chemie (SA6)
5	AG, BG, CG, DG, EG... (R, S, T, U, V...)	water	water		18.0	2680	Chemie (HOH)

Sequence modifications

C, E, G, H, J, L, N, P, R, T, V, X, Z, 2: 301 - 534 (UniProt: O33245)

PDB	External Database	Details
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	730594.2
Non-Polymers*	Number of molecules	137
	Total formula weight	12929.4
All*	Total formula weight	743523.7

*Water molecules are not included.