3MH5

HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protease do	polymer	456	47942.1	2	UniProt (P0C0V0) Pfam (PF13365) Pfam (PF00595)	Escherichia coli	DegP, HtrA
2	C, D (A, B)	DIISOPROPYL PHOSPHONATE	non-polymer		166.2	2	Chemie (DFP)
3	E, F (A, B)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B: 1 - 448 (UniProt: P0C0V0)

PDB	External Database	Details
Arg 449	-	expression tag
Ser 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95884.1
Non-Polymers*	Number of molecules	2
	Total formula weight	332.3
All*	Total formula weight	96216.4

*Water molecules are not included.