3MGH

Binary complex of a DNA polymerase lambda loop mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, C)	DNA polymerase lambda	polymer	329	36736.0	2	UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791)	Homo sapiens (human)	Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2
2	B, F (T, E)	DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3')	polymer	11	3374.2	2
3	C, G (P, F)	DNA (5'-D(*CP*AP*GP*TP*AP*C)-3')	polymer	6	1793.2	2
4	D, H (D, G)	DNA (5'-D(P*GP*CP*CP*G)-3')	polymer	4	1191.8	2
5	I, J, K, L (A, C)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
6	M, N, O, P, Q... (A, T, P, D, C...)	water	water		18.0	361	Chemie (HOH)

Sequence modifications

A, C: 242 - 462 (UniProt: Q9UGP5)
A, C: 472 - 575 (UniProt: Q9UGP5)

PDB	External Database	Details
Lys 463	-	SEE REMARK 999
Gly 464	-	SEE REMARK 999
Glu 470	-	SEE REMARK 999
Thr 471	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	86190.6
Non-Polymers*	Number of molecules	4
	Total formula weight	92.0
All*	Total formula weight	86282.5

*Water molecules are not included.